【摘要】 目的探讨有氧运动训练对原发性高血压患者动脉硬化的影响。方法选取原发性高血压患者155例,分成对照组76例和有氧运动组79例,对照组仅采用常规药物治疗,有氧运动组在常规药物治疗基础上增加有氧运动训练干预12周;观察并比较干预前后两组患者动脉弹性指数(CAVI、ABI)、四肢血压、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)和尿微量白蛋白(U-MA)等指标。结果干预后,有氧运动组左右两侧CAVI值分别为7.76±0.15和7.88±0.15,明显低于干预前的8.87±0.26和8.89±0.22(P<0.05);有氧运动组左右两侧CAVI值干预前后差值均数(下降幅度)分别为1.03±0.07和0.88±0.06,明显高于对照组的0.33±0.09和0.15±0.08(P<0.05)。干预后,有氧运动组四肢血压、TG和TC明显降低(P<0.05),对照组仅四肢收缩压、左下肢舒张压有所下降(P<0.05),且双上肢和右下肢收缩压、双上肢舒张压下降幅度均不及有氧运动组(P<0.05)。结论规律有氧运动训练能明显改善原发性高血压患者动脉弹性。更多还原

【Abstract】 Objective To explore the effect of aerobic exercise training on artery elasticity among patients with essential hypertension. Methods A total of 155 cases of patients with essential hypertension( EH) were selected,and were divided into control group( 76 cases) and aerobic exercise group( 79 cases). Control group was follow routine drug therapy,and aerobic exercise group was follow aerobic exercise training besides the routine therapy for 12 weeks. CAVI,ABI values,limb blood pressure,TG,TC,LDL- C,HDL- C and U- MA were compared before and after the intervention. Results After the intervention,bilateral CAVI values of aerobic exercise group were 7. 76 ± 0. 15,7. 88 ± 0. 15,8. 87 ± 0. 25 and 8. 89 ±0. 22,and lower than those before the intervention( P < 0. 05). The decline range of bilateral CAVI value( the difference between the mean differences before and after the intervention) were 1. 03 ± 0. 07 and 1. 03 ± 0. 06,significantly wider than the control group of 0. 33 ± 1. 97 and 0. 15 ± 0. 08( P < 0. 05). After the intervention,limb systolic pressure,diastolic blood pressure and triglyceride,cholesterol decreased in the aerobic exercise group( P < 0. 05). The limb systolic blood pressure and left limb diastolic blood pressure decreased in the control group after intervention( P < 0. 05),but the decline range was smaller than the aerobic exercise group( P < 0. 05). Conclusion The aerobic exercise training could significantly improve arterial elasticity among patients with essential hypertension.更多还原