【摘要】 目的观察婴幼儿血清铁蛋白测定在营养性缺铁性贫血中的应用。方法 2013年1月至2016年1月在湖南省儿童医院儿童保健科正常体检的缺铁性贫血婴幼儿2 896例。按年龄分为3组,6个月至1岁组1 092例,>1~2岁组980例,>2~3岁组824例。检测不同年龄段婴幼儿血清铁蛋白水平及不同年龄段铁减少、缺铁性贫血和铁缺乏症检出情况。结果 6~12个月和>1~2岁婴幼儿血清铁蛋白水平较>2~3岁显著偏低,差异有统计学意义(P<0.01);6~12个月婴幼儿血清铁蛋白水平与>1~2岁比较差异无统计学意义(P>0.05)。2 896例中铁减少457例(15.8%),缺铁性贫血437例(15.1%),铁缺乏症801例(27.7%)。6~12个月和>1~2岁婴幼儿铁减少检出率显著高于>2~3岁,差异有统计学意义(P<0.017);6~12个月婴幼儿铁减少检出率与>1~2岁比较差异无统计学意义(P>0.017)。随着年龄的增长缺铁性贫血和铁缺乏症检出率逐渐减低,不同年龄段间两两比较差异均有统计学意义(P<0.017)。结论 6个月至3岁婴幼儿中普遍存在铁缺乏现象,为提高家长对婴幼儿铁减少和缺铁性贫血的及早预防,降低贫血的发生,应将血清铁蛋白检测作为婴幼儿期常规体检项目,从而指导家长为婴幼儿及时添加辅食,做到合理膳食,以防止营养性缺铁性贫血的发生。更多还原

【Abstract】 Objective To study the application of serum ferritin detection in children with nutritional iron deficiency anemia.Methods From Jan.2013 to Jan.2016,a total of 2 896 children were found to be with iron deficiency anemia on routine physical examination in Hunan Children’s Hospital.These children were divided into 3groups according to their age:6months to 1year old in group A(1 092children),1to two years old in group B(980children),2to 3years old in group C(824children).Detect serum level of ferritin in these children.The cases of iron decrease,iron deficiency anemia and iron deficiency were also detected.Results The serum level of ferritin in group A and group B was significantly lower than group C,there being statistical difference(P<0.01),but there was no statistical difference between group A and group B(P>0.05).There were 457cases(15.8%)of iron decrease,437cases(15.1%)of iron deficiency anemia and801cases(27.7%)of iron deficiency.The detection rate of iron decrease in group A and B was significantly higher than in group C,and there was statistical difference(P<0.05),but there was no difference between group A and group B(P>0.05).With the child growing up,the detection rate of iron deficiency anemia and iron deficiency decreased gradually,and comparing any two groups among the 3groups,there was statistical difference(P<0.05).Conclusion Iron deficiency is quite common in children between 6months and 3years old.In order to enhance parents’ understanding about the early prevention of iron decrease and iron deficiency anemia and reduce the occurrence of anemia,the serum ferritin detection should be included in the routine physical examinations,and thus the parents can be taught to add solid food in time and to give balanced diet,achieving the aim of preventing nutritional iron deficiency anemia.更多还原