Objective To investigate the changes of TNF-a, IL-6 and IL-2 in peripheral blood and colonic mucosa in ulcerative colitis(UC) patients and their significance. Methods Eighty-five UC patients in our hospital from January 2008 to January 2013 were collected and divided into 3 groups: mild group with 31 cases, moderate group with25 cases and severe group with 29 cases. Twenty-five healthy people having normal colonoscopic results were collected as control group. TNF-α, IL-6 and IL-2 in peripheral blood and col...