【摘要】 目的探讨超声引导下细针穿刺细胞学检查(ultrasound-guided fine needle aspiration biopsy,US-FNAB)对长径≤5 mm甲状腺微小癌的诊断价值。方法回顾性分析我院2013年6月~2015年3月超声引导下细针穿刺294例甲状腺结节患者的298个最大径线≤5 mm的结节,分析穿刺细胞学诊断资料与手术病理及临床随访结果。结果 298个结节中,经细胞学诊断恶性结节172个,良性结节126个;经术后病理学或临床随访证实恶性结节173个,良性结节125个。细针穿刺细胞学检查的敏感度为96.0%(166/173),特异度为95.2%(119/125),准确率为95.6%(285/298),阳性预测值为96.5%(166/172),阴性预测值为94.4%(119/126)。结论 US-FNAB对长径≤5 mm的甲状腺微小癌有很高的应用价值。更多还原

【Abstract】 Objective To investigate the value of ultrasound-guided fine needle aspiration biopsy( FNAB) for the diagnosis of thyroid microcarcinoma smaller than or equal to 5 mm in diameter. Methods A retrospective review was conducted on 298 thyroid nodules ≤5 mm in 294 patients who underwent ultrasound-guided FNAB in our hospital. The diagnostic data obtained from FNAB were compared with those confirmed by surgical pathology and clinical follow-ups. Results Among these 298 thyroid nodules,ultrasoundguided FNAB showed that 172 were malignant and 126 were benign,while surgical pathology and clinical follow-ups confirmed that there were 173 malignant nodules and 125 benign nodules. For ultrasound-guided FNAB,the sensitivity was 96. 0%( 166 /173),the specificity was 95. 2%( 119 /125),the accuracy was 95. 6%( 285 /298),the positive predictive value was 96. 5%( 166 /172),and the negative predictive value was 94. 4%( 119 /126). Conclusion Ultrasound-guided FNAB of thyroid microcarcinoma ≤5 mm in diameter is an effective diagnostic procedure.更多还原