【摘要】 目的了解浙江省仙居县腹泻病患者沙门菌感染率、血清型分布以及各菌株对抗生素的耐药情况,为疾病预防控制和临床治疗提供参考依据。方法采集腹泻患者新鲜粪便,进行增菌、分离培养、生化鉴定、血清分型及药敏试验。结果从426份标本中检出沙门菌26株,检出率为6.10%。共检出9个血清型,鼠伤寒沙门菌为优势菌,其次是婴儿沙门菌、伦敦沙门菌和肠炎沙门菌。26株沙门菌对头孢曲松、丁胺卡那霉素、氧氟沙星3种药物完全敏感,并发现对某些抗生素具有一定耐药性。结论仙居县腹泻病中沙门菌检出率高,血清型分布广泛,多重耐药以鼠伤寒沙门菌和伦敦沙门菌最为显著;头孢类、喹诺酮类抗生素对沙门菌较为敏感,可作为临床首选药物。更多还原

【Abstract】 Objective To investigate the infection rate,serotype distribution and antibiotic resistance of Salmonella in infectious diarrhea patients in Xianju of Zhejiang,so as to provide evidence for disease control and prevention and clinical treatment.Methods The fresh stool samples were collected from infectious diarrhea patients to conduct bacteria enrichment,isolation,biochemical identification,serotyping and antibiotic susceptibility test. Results 26 strains of Salmonella( 9 serotypes) were isolated from 426 samples,the detection rate of which was 6. 10%. Salmonella typhimurium were the dominant bacteria,followed by infant Salmonella,Salmonella enteritidis and Salmonella London. 26 strains of Salmonella were all resistant to ceftriaxone,amikacin,ofloxacin. And it was found to have a certain resistance to some antibiotics. Conclusion Detection rate of Salmonella in infectious diarrhea patients in Xianju is high,serotypes are widely distributed. Multiple drug resistance in Salmonella typhimurium and Salmonella London is more remarkable. Cephalosporins,quinolones was sensitive to Salmonella,which can be used as the preferred clinical medicine.更多还原