【摘要】 目的观察香砂六君子汤合四物汤加减方对动脉粥样硬化的治疗效果。方法 80例存在颈动脉或下肢动脉斑块或狭窄的患者,采用配对分组原则分为治疗组和对照组,各40例。对照组给予基础治疗,治疗组给予基础治疗加服香砂六君子汤合四物汤加减方。比较两组患者总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、C反应蛋白(CRP)、纤维蛋白原(FIB)水平。结果治疗组与对照组治疗前TC[(6.19±1.42)、(6.24±1.65)mmol/L]、TG[(2.89±1.11)、(3.12±1.90)mmol/L]、LDL[(4.14±1.38)、(4.05±1.67)mmol/L]、HDL[(1.01±0.77)、(0.96±0.47)mmol/L]、CRP[(5.32±1.65)、(5.41±1.54)mg/L]、FIB[(4.89±1.11)、(4.14±0.77)g/L]水平比较差异无统计学意义(P>0.05)。治疗后治疗组与对照组TC[(5.11±0.93)、(5.59±1.16)mmol/L]、TG[(1.72±1.51)、(2.38±1.33)mmol/L]、LDL[(2.86±0.73)、(3.38±1.21)mmol/L]、HDL[(1.43±0.35)、(1.13±0.23)mmol/L]、CRP[(3.01±1.76)、(3.70±0.49)mg/L]、FIB[(2.52±0.61)、(3.13±0.68)g/L]水平均优于治疗前(P<0.05),且治疗组优于对照组(P<0.05)。结论香砂六君子汤合四物汤加减方对动脉粥样硬化有改善作用。更多还原

【Abstract】 Objective To observe curative effect by Xiangsha Liujunzi decoction combined with Siwu decoction in modified treatment of atherosclerosis. Methods A total of 80 patients with carotid plaque or lower extremity arterial plaque or stenosis were randomly divided into treatment group and control group, with 40 cases in each group. The control group received basic therapy, and the treatment group received additional Xiangsha Liujunzi decoction combined with Siwu decoction in modified treatment to basic therapy. Comparison was made on total cholesterol(TC), triglyceride(TG), low density lipoprotein(LDL), high density lipoprotein(HDL), C-reactive protein(CRP)and fibrinogen(FIB)levels between the two groups. Results There was no statistically significant difference of TC[(6.19±1.42)and(6.24±1.65)mmol/L], TG[(2.89±1.11)and( 3.12±1.90)mmol/L], LDL [(4.14±1.38)and(4.05±1.67)mmol/L], HDL[(1.01±0.77)and(0.96±0.47)mmol/L], CRP[(5.32±1.65)and(5.41±1.54)mg/L] and FIB[(4.89±1.11)and(4.14±0.77)g/L] levels before treatment between the treatment group and the control group(P>0.05). After treatment, both the treatment group and the control group had better TC[(5.11±0.93)and(5.59±1.16)mmol/L], TG[(1.72±1.51)and(2.38±1.33)mmol/L], LDL [(2.86±0.73)and(3.38±1.21)mmol/L], HDL[(1.43±0.35)and(1.13±0.23)mmol/L], CRP[(3.01±1.76)and(3.70±0.49)mg/L] and FIB[(2.52±0.61)and(3.13±0.68)g/L] than those before treatment(P<0.05), and those in the treatment group were all better than the control group(P<0.05). Conclusion Combination of Xiangsha Liujunzi decoction and Siwu decoction shows improving effect in modified treatment of atherosclerosis.更多还原