【摘要】 目的比较腹腔镜联合胃镜和同期开腹手术治疗胃间质瘤病例的治疗效果。方法回顾性分析2010年1月至2015年3月期间笔者所在医院施行腹腔镜联合胃镜治疗胃间质瘤的56例患者的临床资料,并与同期53例行开腹胃间质瘤手术病例进行对比分析;观察2组患者的一般资料、手术相关指标、手术并发症资料及随访结果。结果 2组患者的一般资料、术中情况、手术后总的并发症率、局部复发及远处转移比较差异均无统计学意义(P>0.05)。腹腔镜联合胃镜组术中发生肿瘤破裂1例,中转开腹1例;开腹组无肿瘤破裂者。2组无围手术期死亡病例,均未发生明显胃出血、吻合口狭窄、吻合口漏等并发症。与开腹组相比,腹腔镜联合胃镜组术中失血量及术后腹腔引流量明显减少,术后肛门排气时间、术后止痛剂使用时间及术后住院时间明显缩短,但住院总费用较高,手术时间较长,其差异有统计学意义(P<0.05)。结论在严格掌握适应证和丰富的开腹胃间质瘤手术经验和熟练的腹腔镜手术技术的基础上,腹腔镜联合胃镜治疗胃间质瘤,能取得与开腹手术同样的疗效,并具有出血少、恢复快等优势。更多还原

【Abstract】 Objective To compare the results of laparoscopic-endoscopic cooperative resection and open surgery for gasric stromal tumor. Methods From January 2010 to March 2015, the clinical data of 56 cases undergoing laparoscopic resection for gasric stromal tumor and 53 cases of traditional operation selected during the same period were retrospectively compared. Results There was no significant difference between two groups in patient’s gender, age, body weight, size of tumor, tumor staging, method of operation, intraoperative conditions, postoperative overall complications, local recurrence, and distant metastasis. There were 1 case with the rupture of tumor and 1 case of open surgery transforming in laparoscopic group. In another group, there was the absence of the rupture of tumors. There was no mortality, stomach bleeding, stenosis or leakage occurred between two groups. In laparoscopic group, there were less operative blood loss and abdominal drainage, shorter time of postoperative anal exhaust time, fewer anodyne, a reduction of hospital stay than in convention operation group. However, laparoscopic resection required greater hospital costs and longer operative time. There were significant differences between two groups(P<0.05). Conclusions With advantages of less blood loss and quicker recovery as compared to conventional operation. Laparoscopic-endoscopic cooperative resection for gasric stromal tumor has similar effect when it is performed by well selection of cases, skilled surgeon with experience on open resection for surgical treatment of gastric stromal tumor.更多还原