【摘要】 石蒜富含重要药用成分加兰他敏,为了优化石蒜中加兰他敏的微波提取工艺,以石蒜为原料、乙醇作提取剂,研究微波功率、料液比、温度、提取时间及次数等单个因素对微波法提取加兰他敏的影响,用正交实验L9(34)确定最佳工艺条件,并与超声波法进行比较。结果显示:用微波法提取石蒜中加兰他敏的最佳条件为料液比1:7,提取温度45℃,微波功率350 W,提取时间7 min;在提取2次的情况下,加兰他敏的提取率达95.8%,产率达0.0549%,粗提取物中加兰他敏含量达15.15%。用微波法提取石蒜中加兰他敏具有提取温度低、时间短、提取率高等优点,整体效果优于超声波法。更多还原

【Abstract】 Lycoris has abundant galanthamine which is an important medical constituent. To optimize themicrowave extraction technique of galanthamine in Lycoris, influences of single factors including themicrowave watt, solid- liquid ratio, temperature, extraction time and times were studied using Lycoris asmaterial and ethanol as extractant. The optimal microwave extraction condition was identified with orthogonaltest L9(34), and compared with the ultrasonic method. Results showed that the best extraction condition was asfollows: the ratio of sample to solvent was 1:7(g:m L), the extraction temperature was 45℃, the microwave wattwas 350 W, the extraction time was 7 min. After sequential extraction for two times under the condition, theextraction ratio and yield of galanthamine were 95.8% and 0.0549%, respectively, and the concentration ofgalanthamine in the extract was about 15.15%. Compared with the ultrasonic method, the microwave methodhad the advantages of lower temperature, less extraction time and higher extraction ratio. The overall effect ofmicrowave extraction was better than that of ultrasonic extraction.更多还原