【摘要】 目的:探讨行为激活疗法合并艾司西酞普兰治疗抑郁障碍患者的疗效。方法:将62例抑郁症患者随机分为研究组和对照组,每组各31例。研究组患者给予行为激活疗法合并艾司西酞普兰治疗;对照组患者单用艾司西酞普兰治疗。分别于治疗前、治疗后以及1年随访时,以HAMD评定两组患者的疗效,以GQOLI-74评定其生活质量,以服药情况评定其治疗的依从性。结果:研究组患者的HAMD减分率和生活质量明显好于对照组(P<0.05)。1年随访前者依从性明显高于后者(P<0.05),前者复发率明显低于后者(P<0.05)。结论:研究组患者的疗效及依从性高于对照组,且远期疗效和预防复发作用好。更多还原

【Abstract】 Objective: To explore efficacy of behavioral activation therapy combined with Escitalopram in treatment of depression. Methods: 62 patients diagnosed as depression were divided into study group( behavioral activation combined with Escitalopram therapy group) and control group( Escitalopram therapy group) with 31 cases in each group by random. Hamilton depression scale( HAMD) was used to evaluate efficacy,general quality of life inventory- 74( GQOLI- 74) was used to evaluate quality of life,and medication was used to evaluate the patients’ compliance. Results: The total scores of HAMD reduced and the scores of GQOLI- 74 increased of study group were better than those of control group significantly( P < 0. 05). After 1 year follow- up,the compliance for study group was much higher than that of control group significantly( P < 0. 05),but the rate of the recurrence of study group was lower than that of control group significantly( P < 0. 05). Conclusions: Behavioral activation combined with Escitalopram therapy compared with Escitalopram therapy can improve the efficacy and compliance significantly,and has a good long- term effectiveness and prevention of recurrence.更多还原