Objective To explore the spatial-temporal characteristics of hemorrhagic fever with renal syndrome(HFRS) inChina's mainland.Methods Demographic information and the annual number of incident HFRS cases in China's mainlandfrom 2004 to 2013 were collected. Retrospective time-space analysis(based on discrete poisson model) was conducted todetect the spatial and spatio-temporal clusters of HFRS cases in Sa TScan(Version 9.1.1) after geographical informationsystem database constructed via Arc GIS software(Version...