【摘要】 严重脓毒症及感染性休克是ICU住院患者常见死亡原因之一。目前,预测严重脓毒症及感染性休克病情预后的生物标记物包括:N末端脑钠肽前体、前心房利钠肽、超敏肌钙蛋白T、降钙素原、C反应蛋白、乳酸、前肾上腺髓质素、促炎因子和抗炎因子等。早期预测病情预后,积极干预,对降低严重脓毒症及感染性休克患者病死率有重要意义。更多还原

【Abstract】 Severe sepsis and septic shock are some of the most common causes of deaths among ICU patients.Current biomarkers that used as early prognostic indicators for patients with severe sepsis or septic shock include N-terminal pro-brain natriuretic peptide,pro-atrial natriuretic peptide,highly sensitive cardiac troponin T,procalcitonin and C-reactive protein,lactate,proadrenomedullin,pro-inflammatory,and anti-inflammatory cytokines.In addition to active medical interventions,early prognostic determination is an important factor that can be used to significantly decrease the mortality rate of patients with severe sepsis and septic shock.更多还原