Objective To investigate the diagnostic value of excreted and secreted antigens of Schistosoma japonicum schistosomula. Methods Cercariae of S.japonicum were used to prepare skin-phase schistosomula via mechanical transformation.The supernatant of a schistosomulum culture was collected and concentrated to prepare the antigens excreted and secreted by schistosomula.Mice were infected with different number of cercariae,and serum samples were collected from mice before infection and at different time post-infe...
***tor schistosomiasis in sentinel mice in environments with a risk of schistosomiasis.血吸虫尾蚴进入宿主皮肤后转变为皮肤期童虫,童虫在宿主体内移行并最终发育成熟。皮肤期童虫的排泄分泌物是最早与宿主免疫系统接触的抗原性物质,诱导宿主产生针对血吸虫的早期免疫反