Objective To explore the clinical significance of changes in levels of expression interleukin 6(IL6)and interleukin 10(IL10)in the malignant transformation of colorectal polyps. Methods Levels of expression of IL6 and IL10mRNA and protein were measured with fluorescence quantitative PCR and immunohistochemistry,and IL6 and IL10expression were compared in normal tissue,colorectal polyps,and colorectal carcinoma. Results The relative quantity of IL6 mRNA expressed in colorectal cancer(2.951±0.474)was signific...
【基金】
山东省医药卫生科技发展计划项目(No.2013WS0335)
【更新日期】
2016-04-14
【分类号】
R735.34
【正文快照】
***mas(1.538±0.077),and villous adenomas(1.577±0.160)(F=89.919,P<0.05).However,the relative quantity ofIL10mRNA did not differ among normal tissue,hyperplastic polyps,and serrated polyps(F=0.175,P>0.05).Nor-mal tissue tested positive for IL10protein at
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