OBJECTIVE To investigate the distribution of virulence genes(pspA,pspC,lytA,lytB,rrgA,nanA,pav,iga,ply and hysA)among Streptococcus pneumoniae isolated from clinical patients so as to provide important reference for the research on the roll of virulence genes in the pathogenesis of the S.pneumoniae and the development of new vaccine.METHODS Totally 20 strains of S.pneumoniae were isolated from patients in Wuxi People′s Hospital from Jan.2013 to Dec.2014.Polymerase chain reaction(PCR)was used to screen for t...