【摘要】 目的对比腹腔镜结直肠癌根治与传统根治手术疗效的临床效果,为今后结直肠癌患者的手术治疗提供依据。方法选取2010年1月至2014年12月126例结直肠癌患者进行试验观察,分为腹腔镜组与开腹组,每组63例。采用SPSS16.0统计学软件进行统计学分析,术中出血量、手术时间、切除肠管长度、术后愈合情况等计量资料用(x珋±s)表示,采用t检验;并发症发生率、复发率和转移率采用χ~2检验,P<0.05时为差异有统计学意义。结果腹腔镜组与开腹组患者的术中出血量为(54.6±20.3)ml和(162.8±80.6)ml;开腹组的手术时间为(172.8±30.2)min,腹腔镜组的手术时间为(252.2±60.4)min,腹腔镜组与开腹组间的差异具有统计学意义(t=5.523,t=6.385,P<0.05)。腹腔镜组与开腹组的肛门排气时间为(2.1±0.3)d和(3.6±0.3)d;腹腔镜组与开腹组的住院时间为(10.9±2.5)d和(19.1±11.9)d,腹腔镜组与开腹组的差异具有统计学意义(t=5.862、6.754,P<0.05);且腹腔镜组与开腹组患者的并发症发生率、复发率和转移率等差异无统计学意义(P>0.05)。结论腹腔镜结直肠癌具有较高的临床疗效,并能够对患者的损伤较小,住院时间短,显著改善患者的预后,能够在临床治疗结直肠癌中推广使用。更多还原

【Abstract】 Objective To compare the clinical efficacy between laparoscopic surgery and traditional radical surgery for colorectal cancer,and to provide perspectives for the treatment of colorectal cancer.Methods 126 patients who had received operation from January 2010 to December 2014 were enrolled in this study. They were divided into a laparoscopic group and an open group,with 63 patients in each group.SPSS16. 0 was used for statistical analysis. Blood loss,operative time,length of bowel resection and postoperative healing were expressed as mean ± SD and were assessed by Student’s t test. The incidence of complications,recurrence rate and metastasis rate were tested by using the Chi-square test. P < 0. 05 was considered statistically significant. Results Blood loss in the laparoscopic group and open group was( 54. 6 ± 20. 3) ml and( 162. 8 ± 80. 6) ml,respectively. The operation time in the laparoscopic group( 252. 2 ± 60. 4) min was longer than that( 172. 8 ± 30. 2) min in the o pen group( t = 5. 523,t = 6. 385,P < 0. 05). The flatus time( 2. 1 ± 0. 3) d in the laparoscopic group was shorter than that( 3. 6 ± 0. 3) d in the open group,and hospitalization time was also shorter in the laparoscopic group( 10. 9 ± 2. 5) d( t value5. 862,6. 754,P < 0. 05). There were no significant differences in the incidence of complications,recurrence rate,and metastasis rate between the two groups( P > 0. 05). Conclusion Laparoscopic resection of colorectal cancer is better,than traditional method and it leads to less trauma to the patients,shorter hospital stay and better prognosis.更多还原