【摘要】 目的:探究中药汤剂四磨汤对功能性消化不良患者的临床治疗效果,以及不良反应情况.方法:选取新疆乌鲁木齐市友谊医院2015-01/2016-01收治的功能性消化不良患者120例作为研究对象,并随机分为研究组(n=60)和对照组(n=60),其中对照组患者予以吗叮啉(多潘立酮片)治疗,研究组患者给予四磨汤治疗,治疗1个月(即1个疗程)后,对比两组临床治疗效果以及不良反应发生情况.结果:经过1个疗程的治疗,两组患者的临床症状总积分均较治疗前显著下降,各组治疗前后差异均具有统计学意义(P<0.05);治疗后研究组患者临床病症总积分显著小于对照组,差异有统计学意义(P<0.05),且研究组痊愈患者占比显著高于对照组,差异有统计学意义(P<0.05);治疗期间,对照组部分患者出现腹部痉挛、嗜睡以及皮疹等不良反应,而研究组患者未见不良反应,研究组不良反应发生率明显小于对照组,差异具有统计学意义(P<0.05).结论:四磨汤治疗功能性消化不良具有起效快、临床治疗疗效显著和不良反应低的优点,值得进行临床推广.更多还原

【Abstract】 AIM: To investigate the clinical efficacy and adverse reactions in patients with functional dyspepsia( FD). METHODS: A total of 120 patients with FD admitted into Urumqi Friendship Hospital,Xinjiang from January 2015 to January 2016 were selected as study objects and randomly divided into the experimental group and the control group,with 60 cases in each group. The control group was given Madinglin( Domperidone)treatment,and the experimental group was treated with Simotang.Both of them received treatment for a month. The clinical treatment effect and adverse reaction were compared between the two groups before and after treatment. RESULTS: After treatment,the total score of clinical symptoms for both groups decreased which was more significantly in experimental group with statistical significant difference when compared with the level before treatment( P < 0. 05). The total score of clinical symptoms from patients of the experimental group decreased more obviously when compared with the control group,there was statistically significant difference( P < 0. 05),and it was found that the proportion of patients cured in the experimental group was higher than the control group,there was statistically significant difference( P<0.05).During the treatment,the control group patients presented abdominal cramps,sleepiness and rash and other adverse reactions,while the study group of patients showed no adverse reaction,study group incidence rate of adverse reaction was significantly lower than that of the control group,there was statistically significant difference( P<0.05). CONCLUSION: Simotang shows rapid and high clinical curative effect and low adverse reaction in the treatment of functional dyspepsia,and it is worth clinical promotion.更多还原