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甲状腺癌中央区淋巴结清除术后乳糜漏的防治

Prevention and treatment of chylous fistula after central lymph node dissection of thyroid cancer

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【作者】 郝伟静于洋郑向前杨晓勇赵敬柱董莉阮先辉彭琛池嘉栋高明

【Author】 Weijing HAO;Yang YU;Xiangqian ZHENG;Xiaoyong YANG;Jingzhu ZHAO;Li DONG;Xianhui RUAN;Chen PENG;Jiadong CHI;Ming GAO;Department of Thyroid and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy;

【机构】 天津医科大学肿瘤医院甲状腺颈部肿瘤科国家肿瘤临床医学研究中心天津市肿瘤防治重点实验室

【摘要】 目的:探讨甲状腺癌中央区淋巴结清除术后乳糜漏发生的原因及有效的防治措施。方法:选取天津医科大学肿瘤医院2013年7月至2015年6月6 127例甲状腺癌中央区淋巴结清除术病例,其中14例患者术后并发乳糜漏。采取全身治疗、局部加压包扎、常压引流、50%葡萄糖注射液或平阳霉素经引流管注入等保守治疗,保守治疗效果不理想时行手术治疗。结果:12例患者行保守治疗后,引流量逐渐减少,至<10 m L/d时拔除引流管;2例患者保守治疗后,引流量未见明显减少,行手术治疗。结论:甲状腺癌中央区淋巴结清除术时应仔细操作以预防乳糜漏的发生,发生后行保守治疗,保守治疗无效时行手术治疗。

【Abstract】 Objective: To discuss the causes and effective measures of prevention and treatment of chylous fistula after central lymph node dissection(CLND) of thyroid cancer. Methods: A total of 6 127 patients who underwent CLND of thyroid cancer in the Tianjin Medical University Cancer Institute and Hospital between July 2013 and June 2015 were analyzed; of which, 14 patients acquired the complication of postoperative chylous fistula. The following conservative treatments were initially performed: systemic therapy, local pressure bandaging, normal pressure drainage, 50% glucose injection, or pingyangmycin injection through a drainage tube. Surgical operation was then conducted when the efficacy of the treatment was poor. Results: After the conservative treatment of the 14 patients,the drainage volume gradually decreased in 12 patients, and surgery was performed on the remaining two patients. Conclusion: The CLND of thyroid cancer must be carefully conducted to prevent postoperative chylous fistula. An active conservative treatment must be the first option when chylous fistula occurs. Surgery must only be performed if the treatment is invalid.

  • 【文献出处】 中国肿瘤临床 ,Chinese Journal of Clinical Oncology , 编辑部邮箱 ,2016年02期
  • 【分类号】R736.1
  • 【被引频次】28
  • 【下载频次】488
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