【摘要】 目的回顾肾上腺皮质腺癌的诊治经验,为肾上腺皮质腺癌术前诊断及综合治疗提供参考。方法以术后病理学诊断为基础,回顾性分析2001年6月至2014年6月于本院接受手术治疗的肾上腺皮质腺癌病例,对其临床表现、内分泌及影像学检查、治疗、随访进行分析,并总结相关文献。结果共有4例患者术后病理证实为肾上腺皮质腺癌,根据ENSAT分期系统,临床Ⅱ期患者1例,其余3例均为临床Ⅲ期。所有患者均经开放手术治疗,术后1例患者接受辅助化疗。所有患者接受门诊及电话随访6~26个月。结论肾上腺皮质腺癌临床发病率低、恶性程度高、易复发、预后差;腹部增强CT可作为首选检查。外科手术为患者的首选治疗方案,即使是术后复发的患者,二次手术治疗效果亦强于单纯化疗。更多还原

【Abstract】 Objective To sum up our experience, explore the significant achievements all over the world, offer recommendations for the diagnosis and treatment of adrenocortical carcinoma. Method Based on the pathologic diagnosis, we reviewed the cases of adrenocortical carcinoma from June 2001 to June 2014. The clinical information, including the clinical manifestations, endocrine tests, imaging evident, treatment and follow-up, were collected and analyzed. Result There were 4 patients pathologically diagnosed of adrenocortical carcinoma. Based on the ENSAT staging system, there was one case of stage Ⅱ, all the others were stage Ⅲ. All patients accepted the surgical treatment, with one patient taking adjuvant radiotherapy after surgery. Follow-up phone calls and outpatient visits were carried out for 6 to 26 months. Conclusion Adrenocortical carcinoma is a rare malignant neoplasm with poor prognosis. Contrast-enhanced CT imaging is the first choice for examination. Surgical operation is the first recommendation for patients of any clinical stage, which is also optional for recurrence of tumor.更多还原