【摘要】 质子泵抑制剂(PPI)是临床预防应激性溃疡中常用的抑酸药,通过作用于抑酸终末步骤而发挥强大的抑酸作用。与其他抑酸药相比,其不良反应较重,易导致原有病情恶化,给患者带来极大痛苦。近年来很多研究发现PPI的使用与肺炎发生密切相关,大致分为与社区获得性肺炎相关及与医院获得性肺炎相关两大类。本文对目前PPI与肺炎关联性的研究进展进行综述。更多还原

【Abstract】 Proton pump inhibitors（PPI） are common acid-suppressing drugs in clinical preventive treatment of stress ulcer.PPI exerts strong acid-suppressing effect via acting on the terminal step of acid suppression.However,compared to other acid-suppressing drugs（H₂ receptor antagonists,for instance）,PPI has more adverse reactions which leads to worse conditions.In recent years,many studies have found close relation between PPI and pneumonia（including community-acquired pneumonia and hospital-acquired pneumonia）.This article reviewed research progress of the relation between PPI and pneumonia.更多还原