【摘要】 目的研究孕妇血清P-亮氨酸氨基肽酶(LAP)检测在异常妊娠中的应用价值,为临床异常妊娠的检测提供参考。方法选择我院2014年2月~2015年4月收治的妊娠产妇作为本次研究的对象,包括异常妊娠及正常妊娠,比较其血清LAP、碱性磷酸酶(ALP)、丙氨酸氨基转移酶(ALT)活性。结果早期妊娠组中,异位妊娠产妇的LAP活性低于正常妊娠者,差异有统计学意义(P<0.05),但两者ALP和ALT的活性差异无统计学意义(P>0.05);中期妊娠组中,先兆流产和正常妊娠产妇的LAP、ALP、ALT活性比较差异无统计学意义(P>0.05);晚期妊娠组中,正常妊娠和多胎妊娠、胆内胆汁淤积症的LAP、ALP、ALT活性比较,差异有统计学意义(P<0.05)。结论孕妇血清P-LAP检测在异常妊娠中具有积极的价值,可有效监测妊娠过程中是否存在异常情况。更多还原

【Abstract】 Objective To study the clinical value of serum P-leucine aminopeptidase(LAP) detection in abnormal pregnancy and to provide reference opinions for the detection of abnormal pregnancy. Methods Pregnant parturient from February 2014 to April 2015 of our hospital were selected as experimental objective,including normal pregnant and abnormal pregnancy parturient.The activity of serum LAP,alkaline phosphatase(ALP) and alanine aminotransferase(ALT) in two groups were compared. Results In early pregnancy,the activity of LAP in ectopic pregnancy group was lower than that of normal pregnancy(P<0.05),but the activity of ALP and ALT between two groups had no obvious difference(P >0.05).In mid pregnancy,the LAP,ALP and ALT between threatened abortion group and normal pregnancy group had no obvious difference(P>0.05).In third pregnancy,the activity of LAP,ALP and ALT between normal pregnancy group and multiple pregnancy group,intrahepatic cholestasis had obvious difference(P<0.05). Conclusion Pregnant serum P-LAP detection has positive determination value in abnormal pregnancy,which can effectively monitor whether there is any abnormal situation during pregnancy.更多还原