【摘要】 目的探讨T2DM患者颈动脉内-中膜厚度(CIMT)与代谢危险因素的相关性。方法 T2DM患者55例,根据CIMT水平分为CIMT正常组(<0.9 mm)和CIMT增厚组(≥0.9 mm),比较两组各项临床和生化指标,分析CIMT增厚与各种代谢危险因素的相关性。结果 55例T2DM患者中,CIMT正常24例(43.6%),CIMT增厚31例(56.4%)。与CIMT正常组比较,CIMT增厚组病程长,SBP高。Logistic回归分析显示,CIMT增厚与病程、WC、SBP等因素呈正相关。结论 CIMT增厚在T2DM患者中非常普遍,其不仅与病程延长和/或增龄相关,且与代谢危险因素的控制水平相关。更多还原

【Abstract】 Objective To investigate the association between carotid intima-media thickness(IMT)and metabolic risk factors in patients with type 2 diabetes(T2DM).Methods 55 patients with T2 DM were enrolled in this study.Based on the value of carotid IMT,the patients were defined as normal carotid IMT(<0.9 mm) and abnormal carotid IMT(≥0.9 mm) groups.The clinical and biochemical parameters were compared between the two groups.The association of abnormal carotid IMT with the clinical and biochemical parameters was analyzed.Results Among 55 patients with T2 DM,normal carotid IMT and abnormal carotid IMT were found in 24 cases(43.6%) and 31 cases(56.4%),respectively.Diabetes duration was significantly longer and systolic pressure was remarkably higher in the abnormal carotid IMT group than in the normal carotid IMT group.Logistic regression analysis revealed that abnormal carotid IMT was positively associated with diabetes duration,waist circumference and systolic pressure.Conclusion Abnormal carotid IMT is common in patients with T2 DM,and is associated with diabetes duration and/or age as well as the control levels of metabolic risk factors.更多还原