【摘要】 目的观察新诊断T2DM患者采用动态血糖监测系统(CGMS)联合胰岛素泵治疗对血糖控制的效果。方法将80例新诊断T2DM患者分为研究组41例,采用CGMS联合胰岛素泵治疗;对照组39例,采用胰岛素皮下注射结合指尖血糖监测治疗。结果研究组FPG、2 hPG和C—RP低于对照组,胰岛β细胞功能指数(HOMA—β)高于对照组(P<0.05)。研究组血糖达标时间[(6.3±1.5)vs(9.6±1.8)d]、低血糖发生次数[(10.5±3.8)vs(28.6±5.8)次]、胰岛素用量[(38±4)vs(43±4)U/d]、血糖波动值[(3.17±1.53)vs(5.24±1.79)mmol/L]均低于对照组(P<0.01)。结论采用CGMS联合胰岛素泵治疗新诊断T2DM患者,有利于进一步精细的调控胰岛素用量,尽快达到降血糖的目的,降糖效果更平稳。更多还原

【Abstract】 Objective To observe the clinical effect of insulin pump therapy combined with continuous glucose monitoring system(CGMS) in newly diagnosed type 2 diabetes(T2DM).Methods80 cases of newly diagnosed T2 DM were divided into treatment group(n = 41,insulin pump therapy combined with CGMS) and control group(n = 39,routine subcutaneous insulin injection therapy combined with fingertip blood glucose monitoring).Results The levels of FPG,2 hPG,and C-RP after treatment were significantly lower in treatment group than in control group,and HOMA-β index was significantly higher in treatment group than in control group(P<0.05).Time of blood glucose reaching target[(6.3± 1.5) vs(9.6±1.8) d],the incidence of hypoglycemia[(10.5 ± 3.8) vs(28.6 ± 5.8) times],insulin dosage[(38±4) vs(43 ± 4) U/d],blood glucose fluctuation value[(3.17±1.53) vs(5.24 ± 1.79)mmol/L]were significantly lower in treatment group than those in control group(P<0.05).Conclusion Insulin pump therapy combined with CGMS is conducive to finely regulate insulin dose and achieve smooth glucose control as soon as possible.更多还原