【摘要】 目的观察中西医结合治疗角膜轻、中度烧伤后角膜上皮损伤的疗效。方法采用阳性药物平行对照方法,将80例角膜烧伤患者按照就诊顺序编号,单号为中药口服联合还原型谷胱甘肽滴眼液治疗组(中西医组);双号为碱性成纤维细胞生长因子(b FGF)滴眼液治疗组(生长因子组),于治疗后1、3、5、7、10及14 d复查,观察两组患者角膜上皮修复情况、症状体征得分和预后。结果两组治疗均能促进角膜上皮的修复,两组疗效之间比较,差异无统计学意义;然而治疗后中西医组的眼干涩以及异物感的症状明显轻于生长因子组,两者之间差异有统计学意义,新生血管的发生率中西医组也明显低于生长因子组。结论中西医结合可促进角膜烧伤后上皮的愈合,并能减轻患者的不适感。更多还原

【Abstract】 OBJECTIVE To observe the effects of corneal epithelial repaire after corneal burn by combined Chinese and western medicine treatment. METHODS A parallel positive controlled scheme was applied in this trial.Specifically, patients were divided into two groups according to their visit sequence, patients consulted in odd numbers were assigned into case group that were treated by combined Chinese and western medicine, while participants visited in even numbers were assigned into control group were treated by basic fibroblast growth factor(b FGF). The therapeutic effects of two groups were observed and compared. RESULTS Two modalities were both effective in repair of corneal epithelium, and there was no significant difference between the two methods. We also found the symptom score of case group was significantly lower than that of control group, the symptoms of dry eye and the astringent and foreign body sensation of patients in the case group were significantly slighter than that in participants of control group, and the incidence rate of neonatal blood vessel was significantly lower than that in group B. CONCLUSIONS The combination of Chinese and western medicine could promote the recovery of corneal epithelium after burn, and could also alleviate the discomfort of patients.更多还原