【作者】
李延；
陶娟；
陈怡洁；
马刚；
于文心；
苏振民；
吴慧玲；
黄雯；
郑罡；
沈玲悦；
刘盛秀；
苑凯华；
刘华绪；
林晓曦；
【Author】
LI Yan;TAO Juan;CHEN Yi-jie;MA Gang;YU Wen-xing;SU Zhen-ming;WU Hui-ling;HUANG Wen;ZHEN Gang;SHEN Ling-yue;LIU Sheng-xiu;YUE Kai-hua;LIU Hua-xu;LIN Xiao-xi;Department of Dermatology,Affiliated Union Hospital,Tongji Medical College,Huazhong University of Science and Technology;Department of Plastic and Reconstructive Surgery,laser cosmetology center,Shanghai Ninth People ’s Hospital,Shanghai Jiaotong University School of Medicine;Department of Plastic Surgery,Children ’s Hospital of Quanzhou City,Fujian Province;Department of Plastic Surgery,the First Affiliated Hospital of Zhejiang University;Department of Dermatology,Huashan Hospital Affiliated to Fudan University;Department of Dermatology,Central Hospital of Xuzhou;Department of oral and maxillofacial and neck tumors,laser cosmetology center,Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine;Department of Dermatology ,the First Affiliated Hospital,Anhui Medical University;Department of Plastic Surgery,General Hospital of Guangzhou Military Command;Department of laser cosmetic surgery,Shandong Provincial Institute of Dermatology and Venereology;Department of Plastic and Reconstructive Surgery,Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine;
【机构】
华中科技大学同济医学院附属协和医院皮肤科；
上海交通大学医学院附属第九人民医院整复外科、激光美容中心；
福建省泉州市儿童医院整形外科；
浙江大学附属第一医院整形科；
复旦大学附属华山医院皮肤科；
徐州市中心医院皮肤科；
上海交通大学医学院附属第九人民医院口腔颌面头颈肿瘤科、激光美容中心；
安徽医科大学一附院皮肤；
广州军区广州总医院整形外科；
山东省皮肤病性病防治研究所暨山东省皮肤病医院激光美容外科；
上海交通大学医学院附属第九人民医院整复外科；
【摘要】 鲜红斑痣(port wine stain,PWS)是一种先天血管畸形,发病率为0.3%~0.5%。鲜红斑痣不会自行消退,随着患者的年龄增长,颜色逐渐加深,皮损增厚甚至形成结节。脉冲染料激光(pulsed dye laser,PDL)是临床治疗的标准方法。然而,只有少数患者能达到完全清除,还有相当一部分患者治疗无效。本文对这类难治性PWS的皮损特征进行总结,并讨论目前治疗选择以及新进展。更多还原
【Abstract】 Being a type of capillary malformation,port- wine stains( PWS) have an incidence of 0. 3 %-0. 5 %. The lesions of PWS will not disappear automatically. Instead,they become darker and thicker with the pass of the time and even progress into nodules in late stage.The pulsed dye laser( PDL) has long been accepted for treating these vascular lesions,but very few patients have achieved a total clearance of PWS with it and a significant number of lesions did not respond to it at all. This review addresses what is now known about lesion-specific characteristics of PDL-resistant PWS as well as discusses current and future treatment options.更多还原
【基金】 国家自然科学基金青年科学基金项目(81602777);上海市卫生系统重要疾病联合攻关项目(2013ZYJB0014)
