【摘要】 目的通过分析2010-2013年梧州市艾滋病(HIV)母婴传播阻断工作监测资料,了解梧州市HIV母婴传播阻断综合模式实施的成效。方法收集梧州市2010-2013年的婚前保健人群预防HIV母婴传播咨询率和抗体检测率、孕产妇预防HIV母婴传播咨询率和抗体检测率、感染HIV孕产妇抗病毒药物应用率、感染孕产妇所分娩婴儿药物应用率、感染HIV孕产妇所分娩婴儿满18个月龄HIV检测率和确诊阳性率、HIV阳性孕产妇人工终止妊娠率监测资料,利用EXCEL 2003和SPSS 16.0进行分析。结果 2010-2013年梧州市婚前保健人群预防HIV母婴传播咨询率分别为99.73%、100.00%、100.00%和100.00%,不同年份间比较,差异有统计学意义(χ2=440.526 8,P<0.05);HIV抗体检测率分别为98.64%、99.86%、100.00%和100.00%,不同年份间比较,差异有统计学意义(χ2=1 852.401 2,P<0.05);孕产妇预防HIV母婴传播咨询率分别为93.70%、99.71%、99.96%和99.98%,不同年份间比较,差异有统计学意义(χ2=10 399.748 5,P<0.05);孕产妇HIV抗体检测率分别为96.52%、99.59%、99.96%和99.98%,不同年份间比较,差异有统计学意义(χ~2=508 6.239 3,P<0.05);感染HIV孕产妇抗病毒药物应用率分别为65.38%、80.77%、94.12%和90.28%,不同年份间比较,差异有统计学意义(χ2=9.698 1,P<0.05);感染HIV孕产妇所分娩婴儿抗病毒药物应用率分别为61.54%、88.89%、100.00%和100.00%,不同年份间比较,差异有统计学意义(χ2=23.256 5,P<0.05);感染HIV孕产妇所分娩婴儿满18个月龄HIV检测率分别为93.75%、88.00%、89.47%和90.63%,不同年份间比较,差异无统计学意义(χ2=0.383 4,P>0.05);感染HIV孕产妇所分娩婴儿满18个月龄HIV确诊阳性率分别为0、0、0和3.45%;HIV阳性孕产妇人工终止妊娠率分别为10.34%、26.32%、21.95%和46.15%,不同年份间比较,差异有统计学意义(χ2=11.818 7,P<0.05)。结论通过实施梧州市HIV母婴阻断全方位多层次多平台合作模式,婚前保健人群预防HIV母婴传播咨询率和抗体检测率、孕产妇预防HIV母婴传播咨询率和抗体检测率、感染HIV孕产妇抗病毒药物应用率、感染孕产妇所分娩婴儿药物应用率、HIV阳性孕产妇人工终止妊娠率均显著升高,在提高人群预防HIV母婴传播的意识、预防青年及育龄妇女感染HIV、减少HIV母婴传播和减少HIV感染婴儿的出生等方面取得了积极成效。更多还原

【Abstract】 Objective To understand the effectiveness of HIV maternal- neonatal transmission block comprehensive mode in Wuzhou city by analyzing the monitoring data of HIV maternal- neonatal transmission block work in Wuzhou city from 2010 to 2013. Methods From 2010 to 2013,the monitoring data of HIV maternal- neonatal transmission prevention consultation rates and HIV antibody detection rates of premarital health care population and pregnant women,antiviral drug application rates of HIV- infected pregnant women,antiviral drug application rates of babies born by HIV- infected pregnant women,HIV detection rate and HIV definitely diagnostic rate of infants at 18 months born by HIV- infected pregnant women,the artificial termination rate of pregnancy of pregnant women with positive HIV in Wuzhou city was collected,then the data was analyzed by Excel 2003 and SPSS 16. 0 software. Results From 2010 to 2013,HIV maternal- neonatal transmission prevention consultation rates of premarital health care population were 99. 73%,100. 00%,100. 00%,and 100. 00%,respectively,there was statistically significant difference among different years( χ~2= 440. 526 8,P < 0. 05); HIV antibody detection rates of premarital health care population were 98. 64%,99. 86%,100. 00%,and 100. 00%,respectively,there was statistically significant difference among different years( χ~2= 1 852. 401 2,P < 0. 05); HIV maternal- neonatal transmission prevention consultation rates of pregnant women were 93. 70%,99. 71%,99. 96%,and 99. 98%,respectively,there was statistically significant difference among different years(χ~2= 10 399. 748 5,P < 0. 05); HIV antibody detection rates of pregnant women were 96. 52%,99. 59%,99. 96%,and 99. 98%,respectively,there was statistically significant difference among different years( χ~2= 508 6. 239 3,P < 0. 05); antiviral drug application rates of HIV- infected pregnant women were 65. 38%,80. 77%,94. 12%,and 90. 28%,respectively,there was statistically significant difference among different years( χ~2= 9. 698 1,P < 0. 05); antiviral drug application rates of babies born by HIV- infected pregnant women were 61. 54%,88. 89%,100. 00%,and 100. 00%,respectively,there was statistically significant difference among different years( χ~2=23. 256 5,P < 0. 05); HIV detection rates of infants at 18 months born by HIV- infected pregnant women were 93. 75%,88. 00%,89. 47%, and 90. 63%, respectively, there was statistically significant difference among different years( χ~2= 0. 383 4, P >0. 05); HIV definitely diagnostic rates of infants at 18 months born by HIV- infected pregnant women were 0. 00%,0. 00%,0. 00%,and3. 45%,respectively; the artificial termination rates of pregnancy of pregnant women with positive HIV were 10. 34%,26. 32%,21. 95%,and 46. 15%,respectively,there was statistically significant difference among different years( χ~2= 11. 818 7,P < 0. 05). Conclusion Through the implementation of HIV maternal- neonatal transmission comprehensive,multi- level,and multi- platform cooperative mode in Wuzhou city,HIV maternal- neonatal transmission prevention consultation rates and HIV antibody detection rates of premarital health care population and pregnant women,antiviral drug application rate of HIV- infected pregnant women,antiviral drug application rate of babies born by HIV- infected pregnant women,HIV detection rate and HIV definitely diagnostic rate of infants at 18 months born by HIV- infected pregnant women,the artificial termination rate of pregnancy of pregnant women with positive HIV were improved significantly. Active results were achieved in the aspect of improving prevention consciousness of HIV maternal- neonatal transmission,preventing HIV infection among adolescents and women of childbearing age,and reducing HIV maternal- neonatal transmission and birth of infants with HIV infection to the greatest extent.更多还原