The subminiature pressure sensor in pressure guidewire used for measuring fractional flow reserve( FFR) in coronary artery is provided with serious problems of temperature and nonlinear drifts,and at present,the hardware method is the only way to compensate. Aiming at the demerits existing in hardware compensation method,such as low compensation accuracy and high cost,etc.,the improved PSO- BP algorithm is proposed for realizing temperature and nonlinear compensation with software. The results of Matlab sim...