【摘要】 目的了解赣州市HIV/AIDS患者免疫水平及疾病进展情况,为其抗病毒治疗提供参考依据。方法将入选的564例HIV/AIDS病例首次血液标本采用流式细胞仪(FACScont)进行CD4~+T淋巴细胞绝对值检测。结果 564例HIV/AIDS患者的CD4~+T淋巴细胞中位数(四分位数间距)为256.00(277.75)个/μl,CD4~+T淋巴细胞绝对值≤200个/μL者占35.28%,201~350个/μL者占32.09%,351~500个/μL者占18.26%,>500个/μL者占14.36%。不同性别HIV/AIDS患者CD4~+T淋巴细胞绝对值的中位数差异无统计学意义(P>0.05),不同年龄和样本来源HIV/AIDS患者CD4~+T淋巴细胞绝对值的中位数差异有统计学意义(P<0.05)。结论赣州市多数HIV/AIDS患者CD4~+T淋巴细胞免疫水平偏低,HIV感染者已经进入发病高峰期,应加强防控措施。更多还原

【Abstract】 Objective To reveal the immune level of HIV/AIDS and the progress of this disease in Gan Zhou,and provide a proof of antiviral treatment. Method In 564 cases with HIV / AIDS patients absolute value of CD4~+T lymphocyte were detected by Flow Cytometry( FACScont). Results The median( interquartile rang) of CD4~+T lymphocyte in 564 cases of HIV / AIDS patients was 256. 00(277. 75) / μl. The percentage of cases with different ranges of absolute value of CD4~+T lymphocyte( ≤200 / μL,201 ~ 350 / μL,351 ~ 500 /μL,> 500 /μL) was respectively 35. 28%,32. 09%,18. 26%,14. 36%.;the difference of median absolute value of CD4~+T lymphocyte in different gender had no statistical significances( P > 0. 05). Different ages and sample source variety were statistically significant( P < 0. 05). Conclusion The immune level of CD4~+T lymphocyte is mostly in a low level during HIV / AIDS,the infected persons are entering the peak period of incidence,so further prevention should be strengthened.更多还原