Objective To observe the clinical and pathological features of cutaneous squamous cell carcinoma(SCC)and actinic keratosis(AK). Methods A retrospective analysis was performed using the data of 17 outpatient cases of squamous cell carcinoma and 45 outpatient cases of actinic keratosis pathologically diagnosed from January 2010 to December 2014. Results Both SCC and AK majorly occur in the aged individuals,and SCC developed in elder person than AK patients. Both SCC and AK lesions exist in the head,face,dista...