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血清胱抑素C、β2微球蛋白检测对早产儿肾功能的评价
Evaluation of Serum Cystatin C and β2 Microglobulin Detection preterm infants Renal Function
【摘要】 目的探讨血胱抑素C(SCys C)、β2微球蛋白(β2-MG)在检测早产儿早期肾功能损伤的诊断价值。方法按出生胎龄将研究对象分成2组,2832周早产儿50例(A组),3337周早产儿50例(B组);对照组为正常足月儿50例。测定3组患儿的SCys-C、β2-MG、尿素氮、肌酐浓度及相关性分析。结果 SCy-C、β2-MG在A组与B组比较、A组与对照组比较有差异(P<0.05);SCys-C、β2-MG之间有相关性(r=0.55)。结论 SCys-C、β2-MG作为检测早产儿肾功能的指标,二者联合检测可为早产儿临床肾功能的检测提供更可靠的指标。
【Abstract】 Objective To discuss of diagnostic value for serum cystatin C(SCys C),β2 microglobulin(β2-MG) in early renal injury in preterm neonates.Method According to gestational age were divided into two groups,and 28-32 weeks premature were 50 cases(group A),33 to 37 weeks premature were 50 cases(group B).Normal full term was 50 cases as control group.Determination of three groups of children SCys-C,beta 2-MG,concentration of urea nitrogen,creatinine,and correlation analysis.Result SCys-C,beta 2-MG in group A and group B in the comparison,A group also had differences compared with control group(P <0.05).There is a correlation between SCys-C and beta 2-MG(r=0.55).Conclusion SCys-C、β2-MG were used as indicators to detect renal function of prematurity,and the joint detection can be premature clinical testing and can provide a more reliable indicator of renal function.
【Key words】 Premature; Renal function; Serum cystatin C; β2 microglobulin;
- 【文献出处】 中国医药指南 ,Guide of China Medicine , 编辑部邮箱 ,2016年14期
- 【分类号】R722.6
- 【被引频次】3
- 【下载频次】36