【摘要】 既往研究发现中性粒细胞与淋巴细胞的比值升高与冠脉造影对比剂肾病发生具有相关性,然而中性粒细胞与淋巴细胞的比值升高是否对患者远期肾功能恶化具有预测价值,目前相关研究较少。本研究入选于我院行冠脉CTA检查患者338例,根据冠脉CTA前患者中性粒细胞与淋巴细胞的比值,将患者分为正常组,轻度升高组及明显升高组,并进行十二个月随访,终点事件为GFR下降超过12mL/min或最终GFR小于60mL/min。研究结果表明中性粒细胞与淋巴细胞的比值升高是冠脉CTA后患者发生远期肾功能不全的危险因素。更多还原

【Abstract】 Previous studies have demonstrated neutrophil to lymphocyte ratio(NLR)have relationship with the occurrence of contrast-induced nephropathy.However,the research on the predictive value of NLR on the happening of CKD among people do CTA exercises is rare.We include 338 patients undergoing CCTA exam.The patients were arranged into three equal groups according to their baseline NLR values normal tertile,NLR higher tertile and NLR highest who were followed at our clinic for one year.The outcome was continuous decrease of GFR>12mL/min between 2007 and 2009 with the last GFR <60mL/min.The research found the result that NLR predicted the long-term renal disfunction in CCTA patients.更多还原