【摘要】 门静脉高压是肝硬化患者最常见的并发症,而门静脉高压所致的食管胃底静脉曲张破裂出血则是肝硬化患者最常见的死亡原因。非选择性β受体阻滞剂是目前用于降低门静脉高压以预防食管胃底静脉曲张破裂出血和再出血的一线药物,非选择性β受体阻滞剂可通过降低门脉血流量,从而降低门脉压力,然而,近年来有报道提示非选择性β受体阻滞剂可增加门脉高压患者的死亡率。本文将对非选择性β受体阻滞剂的作用及其在门静脉高压患者中临床运用做一综述。更多还原

【Abstract】 Portal hypertension is the most common complication in patients with cirrhosis,and variceal hemorrhage caused by Portal hypertension is one of the most important causes of death.Nonselective β-blockers are the first choice for the prevention of variceal hemorrhage and re-bleeding in patients with portal hypertension.It can lower the portal hypertension by reducing the portal blood flow.However,an increased mortality for using nonselectiveβ-blockers has been reported.This article reviewed the effects of nonselective β-blockers and the clinical application of it in patients with portal hypertension.更多还原