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桂西及其周边地区变应性鼻炎儿童过敏原特异性IgE检测分析
Analysis of serum allergen specific IgE in children with allergic rhinitis in western Guangxi and beyond
【摘要】 目的调查桂西及其周边地区变应性鼻炎(AR)患儿的主要过敏原,了解环境、饮食因素与患病之间的相关性。方法应用Mediwiss Allergy Screen系统,检测164例AR患儿的血清总免疫球蛋白E(IgE)和吸入性、食入性过敏原特异性IgE(sIgE)。结果血清总IgE阳性率为91.46%,吸入性过敏原组阳性率为80.49%(户尘螨45.12%、霉菌组合18.90%、蟑螂15.85%、猫狗毛皮屑8.54%),食入性过敏原组阳性率为21.95%(牛奶15.85%、鸡蛋9.76%、牛肉9.15%、芒果为7.93%)。发病前是否接触食物与食入性过敏原阳性率无明显相关性。结论户尘螨是桂西及其周边地区儿童变应性鼻炎最常见的过敏原。
【Abstract】 Objective To investigate the main allergens in children with allergic rhinitis in western Guangxi and its surrounding areas,and to understand the relationship among environments,diet and prevalence rate of allergic rhinitis. Methods A Mediwiss Allergy Screen system was used to detect serum total immunoglobulin E(IgE)level and inhaled/food allergen specific IgE(sIgE)levels in 164 children with allergic rhinitis.Results In 164 children,91.46% of them had positive serum total IgE,80.49% had positive inhaled allergens,the allergens could be listed as follows:house dust mite(45.12%),mould combination(18.90%),cockroach(15.85%),canine and feline scurf(8.54%);the positive rate of food allergen was 21.95%,which could be listed as follows:milk(15.85%),eggs(9.76%),beef(9.15%),mango(7.93%).There was no significant relationship between whether exposure to food before disease onset and prevalence rate of positive-inhaled allergen. Conclusion House dust mite is the most common allergen in children with allergic rhinitis in western Guangxi and its surrounding areas.
- 【文献出处】 右江民族医学院学报 ,Journal of Youjiang Medical University for Nationalities , 编辑部邮箱 ,2016年01期
- 【分类号】R765.21
- 【被引频次】3
- 【下载频次】59