【摘要】 目的探讨百令胶囊联合依那普利对早期2型糖尿病肾病患者的CRP、Homa IR及预后的影响。方法选取我院2015年4月至2016年4月收治的早期2型糖尿病肾病患者110例,随机分为对照组(48例)和研究组(62例)。对照组采用依那普利治疗,研究组采用百令胶囊联合依那普利治疗。对比两组血生化指标(CRP、SCr、UAER、Hb Alc)和胰岛素相关指标(Homa IR、Homaβ、FINS/FPG)及生活质量评分。结果治疗后,两组的CRP、SCr、UAER、Hb Alc及Homa IR、Homaβ、FINS/FPG指标均取得显著改善,但研究组的改善情况均显著优于对照组(P<0.01);研究组的生活质量评分优于对照组(P<0.01)。结论百令胶囊联合依那普利能够显著改善早期2型糖尿病肾病患者的CRP、Homa IR及预后。更多还原

【Abstract】 Objective To explore the effect of bailing capsule combined with enalapril on CRP, Homa IR and prognosis of patients with early type 2 diabetic nephropathy. Methods 110 cases of patients with early type 2 diabetic nephropathy admitted to our hospital from April 2015 to April 2016 were selected and randomly divided into control group(48 cases) and study group(62 cases). The contol group was treated with enalapril, while the study group was treated with Bailing capsule combined with enalapril. The blood biochemical indices(CRP,SCr, UAER, Hb Alc), insulin-related indexes(Homa IR, Homa β, FINS/FPG) and life quality scores were compared between the two groups.Results After treatment, CRP, SCr, UAER, Hb Alc and Homa IR, Homa β, FINS/FPG of both groups significantly improved, but the improvement of the study group was significantly better than that of the control group(P <0.01). The life quality score of the study group was better than that of the control group(P <0.01). Conclusions Bailing capsule combined with enalapril can effectively improve CRP,Homa IR and prognosis of patients with early type 2 diabetic nephropathy.更多还原