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子宫平滑肌舒张药物的临床研究进展
Clinical research progress of relaxation drugs for uterine smooth muscle
【摘要】 目前临床应用及研发中的子宫舒张药物主要有7类:钙通道阻滞药、非甾体类抗炎药、β肾上腺素受体激动剂、催产素受体拮抗剂、NO供体、硫酸镁和孕激素。本文综述了这些药物的作用机制,并比较了近年来主要药物的临床Cochrane分析结果及对胎儿和母亲双方的影响。
【Abstract】 The current uterine relaxation drugs in clinical application and development include seven categories: calcium channel blockers, non- steroidal anti- inflammatory drugs, β adrenergic receptor agonists,oxytocin receptor antagonist, NO donor, magnesium sulfate and progesterone. This article reviewed the action mechanism of a variety of uterine relaxation drugs and compared the efficacy of the drugs and Cochrane analysis effects on the both fetus and mother, to provide the theoretical basis of clinical obstetrics medicine.
【基金】 国家自然科学基金面上项目(81170536)
- 【文献出处】 中国新药与临床杂志 ,Chinese Journal of New Drugs and Clinical Remedies , 编辑部邮箱 ,2016年12期
- 【分类号】R96
- 【被引频次】1
- 【下载频次】166