【摘要】 目的探讨干燥综合征腮腺MSCT特征及临床诊断价值。方法收集54名接受MSCT检查患者,其中包括38名临床确诊干燥综合征患者,并选择26名非干燥综合征患者作为对照组。图像由两位医师分别进行分析,对CT图像信息如腮腺不均质性、脂肪异常沉积、弥漫斑点片钙化、肿大或萎缩、是否合并结节或囊肿改变等进行评价和统计;并对上述指标绘制ROC曲线,明确其诊断效能。结果 38例SS患者腮腺MSCT图像,38例(100%)均表现为腮腺不均质性,36例(94.7%)表现为腮腺脂肪异常沉积,10例(26.3%)表现为双侧腮腺弥漫性斑点钙化灶,11例表现为腮腺肿大,18例腮腺萎缩。ROC曲线显示SD和脂肪异常沉积具有较高的诊断效能,线下面积分别为0.970和0.945,当SD取15.09,诊断SS的敏感度和特异性分别为94.7%和100%;脂肪异常沉积为I级时诊断敏感性和特异度分别为94.7%和96.2%。结论腮腺CT是诊断SS一种可靠、准确的技术。腮腺不均质性、脂肪异常沉积、腮腺弥漫性斑点钙化对SS诊断具有较高的价值。更多还原

【Abstract】 Objective To discuss the diagnostic accuracy and MSCT features of the parotid gland in Sj9gren’s syndrome( SS)patients. Methods MSCT scans were performed in 54 patients,including 38 patients confirmed SS and 22 symptomatic controls without SS. The CT findings of heterogeneity,abnormal diffuse fat tissue deposition,diffuse punctate calcification,swelling or atrophy,nodularity or cystic changes of the parotid gland were analyzed by two independent blinded readers. Diagnostic performance and receiver operating characteristics curves were calculated. Results On CT imaging of parotid glands,of 38 SS cases,38( 100%) cases displayed heterogeneity,36( 94. 7%) caes displayed abnormal diffuse fat tissue deposition,10 cases( 26. 3%)displayed diffuse punctate calcification( sensitivity; specificity 100%),11 cases demonstrated the parotid gland swelling and 18 cases demonstrated atrophy. ROC showed SD and abnormal diffuse fat tissue deposition had higher diagnostic effect. The areas under the receiver operating characteristics curves of SD and abnormal diffuse fat tissue deposition were 0. 970( P = 0. 000) and0. 945( P = 0. 000). When SD was 15. 09,the sensitivity and specificity were 94. 7% and 100%; and abnormal diffuse fat tissue deposition was stage I,the the sensitivity and specificity were 94. 7% and 96. 2%. Conclusion Parotid CT is accurate and reliable in the diagnosis of Sj9gren’s syndrome. Heterogeneity,abnormal diffuse fat tissue deposition,and diffuse punctate calcification are specific for Sj9gren’s syndrome.更多还原