【摘要】 目的:研究犬急性心房颤动模型的建立。方法:取24条健康成年杂种犬,随机均分为单纯快速心房起搏组(RAP组)、单纯快速静脉输液组和RAP+快速静脉输液组,尝试建立犬急性房颤模型,比较各组房颤诱发率和房颤持续时间。结果:与RAP组、单纯快速静脉输液组比较,RAP+快速静脉输液组房颤诱发率(0%比0%比62.5%)和房颤平均持续时间[0比0比(115.68±135.87)s]均显著升高,P均<0.01。结论:联合快速心房起搏+快速静脉输液可成功建立心房颤动模型。更多还原

【Abstract】 Objective:To study establishment of canine acute atrial fibrillation(AF)model.Methods:A total of 24 healthy adult mongrel dogs were selected,randomly and equally divided into pure rapid atrial pacing group(RAP group),pure rapid intravenous infusion group and RAP + rapid intravenous infusion group,then canine acute AF model was tried to establish in each group using corresponding method.Inducible rate and duration of AF were compared among three groups.Results:Compared with RAP group and pure rapid intravenous infusion group,there were significant rise in inducible rate(0% vs.0% vs.62.5%)and mean duration[0vs.0vs.(115.68±135.87)s]of AF in RAP + rapid intravenous infusion group,P<0.01 all.Conclusion:Neither pure rapid atrial pacing nor rapid intravenous infusion could induce atrial fibrillation successfully.Combination of both can establish atrial fibrillation model.更多还原