【摘要】 目的:研究基于运动负荷试验评估的个性化有氧运动对急性心肌梗死(AMI)患者心功能与心理状态的疗效。方法:选择80例恢复期的AMI患者为研究对象,采用随机数字表法,患者被均分为常规治疗组(40例,接受常规药物治疗)和运动组(40例,在常规治疗组基础上接受基于运动负荷试验评估的个性化有氧运动)。比较两组患者干预前、干预12周后的血清高敏心肌肌钙蛋白I(hs-cTnI)和肌酸激酶同工酶(CK-MB)水平,左室射血分数(LVEF)、每博量(SV)、左室短轴缩短率(LVFS)、室壁增厚率(△T)、室间隔运动幅度(AIS),以及焦虑自评量表(SAS)和抑郁自评量表(SDS)评分。结果:与干预前比较,干预12周后两组的血清hs-cTnI和CKMB水平均明显降低,SAS和SDS评分亦均显著降低;LVEF,SV,LVFS,△T和AIS均显著升高(常规治疗组的LVEF除外),P<0.05或<0.01;且与常规治疗组比较,运动组血清hs-cTnI[(9.31±1.04)ng/L比(5.89±0.72)ng/L]和CK-MB水平[(11.34±1.25)U/L比(8.41±1.01)U/L];SAS[(51.34±6.54)分比(42.32±5.29)分]和SDS[(50.23±6.92)分比(43.86±6.03)分]评分降低更显著,LVEF[(57.12±6.67)%比(62.32±7.34)%],SV[(62.45±7.13)ml比(69.18±7.84)ml],LVFS[(23.93±2.96)%比(28.45±3.12)%],△T[(28.51±3.41)%比(34.52±4.87)%]和AIS[(9.56±1.02)mm比(12.45±1.46)mm]升高更显著,P<0.05或<0.01。结论:基于运动负荷试验评估的个性化有氧运动能够减轻心肌细胞损伤、改善心脏功能、缓解负面情绪,促进患者迅速康复。更多还原

【Abstract】 Objective:To study therapeutic effect of personalized aerobic exercise based on exercise load test assessment on heart function and psychological state in patients with acute myocardial infarction(AMI).Methods:According to random number table,a total of 80 AMI patients during recovery period were randomly and equally divided into routine treatment group(n=40,received routine drug therapy)and exercise group(n=40,received personalized aerobic exercise based on exercise load test assessment on the basis of routine treatment group).Serum levels of high-sensitivity cardiac troponin I(hs-cTnI)and creatine kinase isoenzyme MB(CK-MB),and left ventricular ejection fraction(LVEF),stroke volume(SV),left ventricular fractional shortening(LVFS),ventricular wall thickening rate(△T),motion amplitude of interventricular septum(AIS),and scores of self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were compared between two groups before and after 12-week intervention.Results:Compared with before intervention,there were significant reductions in serum levels of hs-cTnI and CK-MB,and scores of SAS and SDS;and significant rise in LVEF,SV,LVFS,△T and AIS in both groups after12-week intervention(except LVEF of routine treatment group),P<0.05 or<0.01;compared with routine treatment group,there were significant reductions in serum levels of hs-cTnI[(9.31±1.04)ng/L vs.(5.89±0.72)ng/L]and CK-MB [(11.34±1.25)U/L vs.(8.41±1.01)U/L],in scores of SAS[(51.34±6.54)scores vs.(42.32±5.29)scores]and SDS[(50.23±6.92)scores vs.(43.86±6.03)scores];and significant rise in LVEF [(57.12±6.67)% vs.(62.32±7.34)%],SV [(62.45±7.13)ml vs.(69.18±7.84)ml],LVFS[(23.93±2.96)% vs.(28.45±3.12)%],△T [(28.51±3.41)% vs.(34.52±4.87)%]and AIS[(9.56±1.02)mm vs.(12.45±1.46)mm]in exercise group,P<0.05 or<0.01.Conclusion:Personalized aerobic exercise based on exercise load test assessment can reduce myocardial cell injury,improve cardiac function,relieve negative emotions and promote patients’ rehabilitation rapidly.更多还原