Transcriptional Responses of Innate Immunity Related mRNAs after Infection of Embryonated Chicken Eggs with Newcastle Disease Viruses of Variant Virulence and Doses
Newcastle disease virus(NDV)is the pathogen of Newcastle disease(ND),which causes serious economic losses to poultry industry.For a better understanding of innate immune response in the pathogenesis of NDVs,SPF chicken embryos were infected with a virulent NDV strain and an avirulent vaccine strain-LaSota,respectively,with different infection doses set for both viruses.At the early stage of viral infection,the dynamics of viral proliferation and the transcriptional level of innate immune-related molecules w...