【摘要】 目的:分析当前宿迁地区育龄期男性精液质量情况和不孕不育间的关系。方法:统计分析2012年7月至2014年7月1068例来我院咨询有生育愿望的男性精液,用精液自动分析仪分析精液密度、活率、活力和精子运动速度,Diff-Quik法染色观察精子形态,计数精子畸形率。随访1年统计不孕不育发生率,进行相关分析。结果:22例(2.06%)无精子,56例(5.24%)极弱精子症,123例(11.52%)弱精子症;181例密度小于20.0×106m L(16.95%);110例(10.30%)活率低于20.0%;228例(21.35%)精子活力(a+b)级低于20.0%以下;179例(16.76%)畸形率在95.1%以上;184例(17.23%)平均曲线速度(VCL)小于10.0μm/s。共有96例(8.99%)诊断为不孕不育,50例(4.68%)考虑与男性精液质量有关。相关分析可知,不孕不育与精液数量、活率、(a+b)级精子率和畸形率呈正相关(P<0.05)。多因素回归分析可知,精液活率和活力是不孕不育的独立危险因素(P<0.05)。结论:初步了解宿迁地区育龄期男性精液质量,为不孕不育工作参考依据,在经济相对落后的江苏苏北地区,孕前精液常规检查十分必要。更多还原

【Abstract】 Objectives: To analyze the relationship between semen quality of males at child- bearing age inSuqian and infertility. Methods: 1068 males treated in our hospital for fertility from July 2012 to July 2014 were selected and the semen density,live rate,motility and sperm velocity was tested by semen automatic analyzer; sperm morphology was observed with diff- Quik staining to count sperm deformity rate. The correlation between semen quality and infertility was analyzed in one year follow- up. Results: There were 22 cases of azoospermia( 2. 06%),56 cases of severe asthenospermia( 5. 24%) and 123 cases of asthenospermia( 11. 52%). The density of 181 cases was less than 20. 0 × 106ml( 16. 95%); live rate of 110 cases was less than 20. 0%( 21. 35%); motility a + b of 228 cases was below 20. 0%( 21. 35%); abnormality rate of 179 cases was more than 95. 1%( 16. 76%); average curve velocity( VCL) of 184 cases was less than 10. 0um/s( 17. 23%). There were in all 96 cases diagnosed as infertility( 8. 99%),50 cases of which were referred to semen quality. The semen number,live rate,motility a + b and abnormality rate were all related to infertility( P < 0. 05) and the live rate and motility a+ b were independent risk factors of infertility( P < 0. 05). Conclusions: Preliminary understanding of semen quality at child- bearing age in Suqian area provides reference to the treatment of infertility,which is important for pre- semen routine examination in north of Jiangsu.更多还原