【摘要】 [目的]探讨肺癌患者发生淋巴结转移的规律及影响淋巴结转移的因素。[方法]对既往行肺癌根治性切除术治疗的209例患者进行回顾性分析,对发生淋巴结转移的分布规律及其影响因素进行统计分析。[结果]209例患者,共清扫淋巴结974枚,其中发生淋巴结转移223枚(22.90%),发生淋巴结转移的患者有81例(38.76%)。淋巴结转移率较高的组分别为第11组(30.43%)、第4组(28.00%)、第3组(27.45%),淋巴结转移率较低的组分别为第9组(10.59%)、第1组(14.71%)、第8组(16.00%)。肿瘤的病理类型为腺癌(OR=1.892)、中央型肺癌(OR=1.528)、低分化程度(OR=1.633)是肺癌患者发生淋巴结转移的危险因素(P<0.05),与患者是否吸烟关系不密切(P>0.05)。[结论 ]淋巴结转移主要与病理类型、病灶部位、分化程度有关,淋巴结转移规律分析有利于为手术患者术中扫除淋巴结和放疗患者靶区规划提供参考依据。更多还原

【Abstract】 [Objective] To investigate the risk factors of lymph node metastasis in patients with lung cancer.[Methods] Clinical data of 209 patients with lung cancer undergoing radical resection were retrospectively analyzed.[Results] Total 974 lymph nodes were dissected in 209 patients,and 223 of them(22.90%)from 81 patients(38.76%)were confirmed as metastatic.Most commonly involved lymph nodes were level 11(30.43%),followed by levels 4(28.00%)and 3(27.45%);and level 9 was least involved(10.59%),then levels 1(14.71%) and 8(16.00%).Logistic regression analysis showed that adenocarcinoma(OR=1.892,P<0.05),central type(OR=1.528,P <0.05) and low differentiation degree(OR =1.633,P <0.05) were risk factors of lymph node metastasis in patients with lung cancer.[Conclusion] The lymph node metastasis in lung cancer is mainly related to the pathological type,tumor location and differentiation degree.更多还原