【摘要】 目的了解2008-2015年盐城市手足口病的三间分布规律,为手足口病预防提供理论依据。方法通过中国疾病预防控制信息系统,收集2008-2015年盐城市全部手足口病病例信息,采用描述性研究法对监测数据进行分析。结果本地区2008-2015年共报告手足口病44 962例,平均发病率为75.06/10万。2008-2015年发病率分别为11.45/10万、60.46/10万、50.41/10万、98.54/10万、100.38/10万、78.16/10万、147.63/10万和53.42/10万,呈"峰谷"年状态。季节上,每年存在一大一小两个流行高峰,大流行高峰4-6月份,小流行高峰11月-次年1月份。亭湖区为高发地区(约占35.49%),其周边为次高发区,北部地区为低发区。人群分布上,以1~3岁人群为主要发病人群(约占71.03%);男性明显多于女性,性别比约为1.77∶1;以散居儿童为主(约占75.98%),托幼儿童次之。本地区主要流行肠道病毒毒株为EV71与Cox A16,交替流行,2~3年为一个波动周期。结论盐城市手足口病发病时间时间存在两个流行高峰,地区分布差异大,3岁以下散居儿童为重点人群,建议在发病高峰时期针对重点地区、重点人群进行手足口病防控。更多还原

【Abstract】 Objective To investigate the distribution of HFMD during 2008-2015 in Yancheng,and to provide scientific evidence for prevention and control of the disease. Methods We collected all the hand-foot-mouth disease cases during2008-2015 in Yancheng through the China Information System for Disease Control and Prevention,then analyzed the monitoring data by descriptive epidemiology methods. Results 44 962 cases of hand-foot-mouth disease totally were reported in this region,and the average incidence was 75. 06 /100,000. The incidences from 2008 to 2015 were 11. 45 /100,000,60. 46 /100,000,50. 41 /100,000,98. 54 /100,000,100. 38 /100,000,78. 16 /100,000,147. 63 /100,000 and 53. 42 /100,000,respectively,presenting a " peak-valley" state. There were two epidemics every year with one large and one small peak.The large peak was from April to June,and the small peak was from November to January of the following year. The incidence in Tinghu District was the highest( about 35. 49%),its surrounding was the second high,and the incidence in northern region was the lowest. The main cases were among 1-3 years old( accounting for about 71. 03%). The incidence of a male was higher than that of female,and the sex ratio was 1. 77: 1. The incidence in scattered living children was the highest( about 75. 98%),more than that in kindergarten children. The major epidemic enterovirus strains were EV71 and Cox A16 in this region,which was epidemic alternatively,and the fluctuation period was 2 to 3 years. Conclusion There are two epidemic peaks of hand-foot-mouth disease in Yancheng,and the distribution between regions is different dramatically. The scattered living children under the age of 3 are the main targeted population. It suggests that during the peak it’s necessary to do prevention and control work for the hand foot and mouth disease in the focused areas and the targeted population.更多还原