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徐州地区女性不孕症影响因素的病例对照研究

Case control study on the influencing factors of female infertility in Xuzhou

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【作者】 石月孙莉莉丁昕娄荷清丁晓帆吴秀娟徐莉春胡振兴张训保

【Author】 SHI Yue;SUN Li-li;DING Xin;LOU He-qing;DING Xiao-fan;WU Xiu-juan;XU Li-chun;HU Zhen-xing;ZHANG Xun-bao;School of Public Health,Xuzhou Medical College;

【机构】 徐州医学院公共卫生学院徐州医学院附属妇幼保健院

【摘要】 目的探讨女性不孕症的影响因素,为疾病的早期预防提供科学依据。方法采用病例对照研究对配对的242例病例组和242例对照组进行统一的问卷调查,经过单因素和多因素条件Logistic回归分析筛选出女性不孕症的影响因素。结果内分泌疾病(OR=5.393)、月经不规律(OR=3.507)、手术史(OR=3.494)、精神状态不佳(OR=2.666)、不良生活方式(OR=2.608)、妇科感染(OR=2.285)、肥胖症(OR=1.972)、自然流产(OR=1.904)、痛经史(OR=1.864,)、药物减肥史(OR=1.670)。结论内分泌疾病、月经不规律、手术史、精神状态不佳、不良生活方式、妇科感染、肥胖、自然流产、痛经、药物减肥史是女性不孕症的危险因素;积极治疗内分泌疾病和妇科感染,适度的体育锻炼、良好的生活习惯可能减少不孕症的发生。

【Abstract】 Objective The study aimed to explore the influencing factors for female infertility,so as to provide a scientific reference for early prevention of the disorder. Methods A case- control study was conducted on 242 infertility cases and 242 matching controls by using a unified questionnaire survey,and the influencing factors for female infertility were determined by univariate and multivariate conditional Logistic regression analyses. Results The influencing factors included endocrine disorder( OR = 5. 393),irregular menstruation( OR = 3. 507),history of surgery( OR = 3. 494),poor mental condition( OR = 2. 666),poor lifestyle( OR = 2. 608),gynecological infection( OR = 2. 285),obesity( OR = 1. 972),miscarriage( OR = 1. 904),dysmenorrheal( OR = 1. 864),and drug- associated weight loss( OR = 1. 670). Conclusion The risk factors for female infertility include endocrine disorder,irregular menstruation,history of surgery,poor mental condition,poor lifestyle,gynecological infection,obesity,miscarriage,dysmenorrheal and drug- associated weight loss. Active treatment of endocrine disorders and gynecological infections,moderate exercise,and good living habits may reduce the incidence of infertility.

【基金】 国家自然科学基金(30872143);江苏省普通高校研究生科研创新计划(KYLX14-1458)
  • 【文献出处】 现代预防医学 ,Modern Preventive Medicine , 编辑部邮箱 ,2016年10期
  • 【分类号】R711.6
  • 【被引频次】15
  • 【下载频次】242
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