【摘要】 循环肿瘤细胞(circulating tumor cells,CTCs)是脉管中的肿瘤细胞,被认为是肿瘤血液转移的关键步骤之一。循环肿瘤细胞的检测对于肿瘤的诊断、治疗和预后判定都具有非常重要的意义,因其稀缺性及异质性其检测方法一直是肿瘤研究的热点。本文从CTCs生物学行为、检测方法方面综述了CTCs临床应用的最新研究进展。更多还原

【Abstract】 Circulating tumor cells(CTCs) are the tumor cells in vessel, and considered as the key step in tumor blood metastasis.Detection of CTCs in cancer patients plays very important roles in diagnosis, treatment and prognosis. The heterogeneity and scarcity of CTCs make it very difficult in detection. In this paper, we reviewed the latest research progress in basic and clinical applications of CTCs.更多还原