【摘要】 目的探讨马鞍山市妇女孕前体质指数和孕期增重与妊娠期高血压疾病的关联。方法 2013年5月—2014年9月,在安徽省马鞍山市妇幼保健院招募初次建卡的孕妇(孕周≤14周),建立以孕妇人群为基础的队列并随访至分娩。孕早、中、晚期分别填写《孕产期母婴健康记录表》;测量孕妇的身高、体重和血压并检测尿蛋白。结果 3219名单胎活产儿孕妇的妊娠期高血压疾病发生率为6.09%(196/3219),其中子痫前期的发生率为1.77%(57/3219)。二分类Logistic回归模型分析结果显示,在调整混杂因素后,孕前超重、孕前肥胖及孕期过度增重是妊娠期高血压疾病的危险因素,其OR值分别为2.33(95%CI 1.56~3.47)、7.85(95%CI 4.65~13.24)和1.86(95%CI 1.24~2.79)。结论孕前超重或肥胖和孕期过度增重可增加妊娠期高血压疾病的发病风险。更多还原

【Abstract】 Objective To evaluate the associations between pregnancy body mass index( BMI),gestational weight gain( GWG) and the risk for hypertensive disorder complicating pregnancy( HDCP). Methods In this prospective cohort study,subjects who had their first prenatal examination( gestational age ≤ 14 weeks) at Ma’anshan Maternal and Child Health Care Center were recruited under informed consent,from May16, 2013 to September 11, 2014. All the information were collected through questionnaires,height,weight and maternal blood pressure were measured,and urine protein was detected in the first,second,and third trimester of pregnancy. Results The incidence of HDCP was 6. 09%( 196 /3219),and preeclampsia was 1. 77%( 57 /3219).After adjusting confounding factors,results in Logistic regression analysis showed thatprepregnancy overweight and obesity, weight gain more than recommended during pregnancy were the risk factor of HDCP,the adjusted odds ratios( 95% CI) were 2. 33( 1. 56- 3. 47),7. 85( 4. 65- 13. 24) and 1. 86( 1. 24- 2. 79),respectively. Conclusion Prepregnancy overweight, obeisity, weight gain more than recommended during pregnancy were associated with increased risk of HDCP.更多还原