【摘要】 目的探讨噻托溴铵(Tio)、布地奈德/福莫特罗(Bud/Form)及其联合治疗对D组稳定期慢性阻塞性肺疾病患者C反应蛋白(CRP)水平的影响。方法 D组稳定期慢性阻塞性肺疾病患者,随机分为Tio组、Bud/Form组以及联合治疗组,比较治疗前后患者外周血CRP水平。结果 Tio组受试者治疗前后外周血CRP水平变化无差异。Bud/Form组及联合治疗组受试者治疗后外周血CRP水平下降。结论与单用Tio相比,Bud/Form单用或者联用Tio能够一定程度地降低D组稳定期慢性阻塞性肺疾病患者的CRP水平。更多还原

【Abstract】 Objective To investigate the effects of tiotropium(Tio)and/or budesonide/formoterol(Bud/Form) on C-reactive protein(CRP)levels in COPD patients of group D. Methods Stable COPD patients were randomized into three groups to receive inhaled therapy,Tio,Bud/Form,Tio+Bud/Form. CRP concentrations were measured before randomization and during the treatment. Results Group Tio :there was no differences of CRP levels between the baseline and during the treatment. Group Bud/Form and Group Tio+Bud/Form :CRP levels declined after treatment. Conclusion Compared with Tio,Bud/Form alone or in combination with Tio reduced CRP levels in stable COPD patients of group D.更多还原