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光动力疗法联合CO2激光治疗尖锐湿疣78例临床观察

The Clinical Investigation of ALA-Photodynamic combined with CO2 Laser in Treating Condyloma Acuminatum

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【作者】 于娜李铮马俊红王昕

【Author】 YUNa;LIZheng;MA Junhong;WANG Xin;Department of Dermatology,the First Hospital of Tsinghua University;

【机构】 清华大学第一附属医院皮肤科

【摘要】 目的探讨艾拉-光动力疗法联合CO2激光治疗尖锐湿疣(CA)的临床疗效。方法回顾性分析78例CA,将其分为CO2激光组(n=30)与联合治疗组(n=48),联合治疗组患者采用CO2激光去除显性疣体,然后采用ALA-PDT,每周1次,连续3次,CO2激光组单用CO2激光治疗,治疗结束后1个月、2个月、3个月各随访1次,观察末次随访两组患者的临床治愈率和复发率。结果联合治疗组患者治愈率为77.08%,激光组患者治愈率为33.33%,联合治疗组患者治愈率明显高于激光治疗组(P<0.05)。结论 ALA-PDT联合CO2激光治疗CA优于单纯CO2激光,可作为首先治疗方法。

【Abstract】 Objective To investigate the clinical efficacy of CO2 laser combined with ALA-photodynamic in treatment of patients with condyloma acuminatum. Methods A retrospective analysis of 78 cases CA,which were divided into CO2 laser group(n=30) and combined treatment group(n=48). In combined treatment group,the dominant warts were firstly removed by CO2 laser,then treated with ALA-PDT in combined treatment group,one times a week,for three consecutive times; And in CO2 laser group,the CA were treated with CO2 laser alone. The curative effect and the recurrence rate after treatment 1,2,3 months follow-up were observed,respectively. Results The cure rate of the combined treatment group was 77.08%,which was significantly higher than cure rate of the CO2 laser group(33.33%)(P < 0.05). Conclusion The method of CO2 laser combined with ALA-photodynamic is better than that of CO2 laser only,and that is the preferred method of treatment of genital wart.

  • 【文献出处】 中国卫生标准管理 ,China Health Standard Management , 编辑部邮箱 ,2016年16期
  • 【分类号】R752.53
  • 【被引频次】5
  • 【下载频次】41
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