【摘要】 目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对夜间心绞痛的影响及有效治疗的方法。方法对39例阻塞性睡眠呼吸暂停低通气综合征合并夜间心绞痛患者给予经鼻持续正压通气治疗,采用多导睡眠监测系统进行整夜睡眠监测,比较治疗前后指标改善及症状改善情况。结果患者治疗后睡眠呼吸暂停低通气指数、心肌缺血发作率、心肌梗死发作率、心电图异常率降低(P<0.05),夜间最低血氧饱和度、血压控制良好率增加(P<0.05),夜间心绞痛发作次数减少(P<0.05),左室射血分数改善差异无统计学意义(P>0.05)。结论阻塞性睡眠呼吸暂停低通气综合征诱发加重夜间心绞痛,经鼻持续正压通气治疗可改善阻塞性睡眠呼吸暂停低通气综合征合并夜间心绞痛患者的症状。更多还原

【Abstract】 Objective To investigate effect and effective treat methods of patients with obstructive sleep apnea hypopnea syndrome and nocturnal angina. Methods 39 patients with obstructive sleep apnea hypopnea syndrome and nocturnal angina treated by nasal continuous positive airway pressure. Sleep monitoring was carried out by multi-guide sleep monitoring system. Improvement of indicators and disorders were compared before and after treatment. Results Sleep apnea hypopnea index,myocardial ischemic attack rate,myocardial infarction attack rate,ECG abnormal rate decreased significantly after treatment(P< 0.05). Nocturnal lowest blood oxygen saturation,blood pressure control rate increased significantly after treatment(P < 0.05). Nocturnal angina attack frequency reduced significantly after treatment(P < 0.05). Improvement of left ventricular ejection fraction was not significant(P > 0.05). Conclusion Obstructive sleep apnea hypopnea syndrome can induce exacerbation of nocturnal angina. Nasal continuous positive airway pressure therapy can improve the symptoms of patients with obstructive sleep apnea hypopnea syndrome and nocturnal angina.更多还原