【摘要】 目的评价西酞普兰治疗广泛性焦虑症的临床疗效和副反应。方法将76例符合CCMD--3诊断标准的广泛性焦虑症患者,随机分为两组,分别应用西酞普兰(38例)、氯硝安定(38例)进行对照治疗,疗程8周。采用焦虑自评量表(SAS)、Hamilton焦虑量表(HAMA)和副反应量表(TESS)评定疗效和副反应。结果西酞普兰与氯硝安定对广泛性焦虑症均有显著疗效,两组间疗效差异无显著性(P>0.05),西酞普兰组副反应明显少于氯硝安定组(P<0.01)。结论西酞普兰治疗广泛性焦虑症安全有效,副反应少。更多还原

【Abstract】 Objective To evaluate the efficacy and side effects of citalopram in the treatment of general anxiety disorder.Methods 76 patients who met the criteria of CCMD-3 for generalized anxiety disorder were randomly assigned into citalopram group and clonazepam group for treatment of 8 weeks.The effects and side effects of two groups were assessed by HAMD,SAS and TESS. Results Both drugs had marked efficacy in the treatment of generalized anxiety disorder. Conclusion Citalopram is a safe and efficient drug with fewer side effects for the treatment of generalized anxiety disorder.更多还原