【摘要】 目的探讨新疆喀什地区维吾尔族和汉族胆囊结石形成时脂代谢异常的特点,并探讨其民族差异。方法回顾性收集240例在我院确诊胆囊结石患者进行血脂四项指标测定,其中维族120例,汉族120例,同时检测240例(维汉各120例)健康体检者的血脂四项指标作为对照。结果胆囊结石患者组血清胆固醇、甘油三酯、低密度脂蛋白显著高于对照组(P<0.05),血清高密度脂蛋白(HDL-C)显著低于对照组(P<0.05),差异具有统计学意义。维吾尔族胆囊结石患者组血清胆固醇、甘油三酯、低密度脂蛋白高于汉族胆囊结石患者组(P<0.05),血清高密度脂蛋白(HDL-C)显著低于汉族组(P<0.05),差异具有统计学意义。结论血清TC、TG、LDL浓度升高,HDLC浓度降低等脂代谢异常是胆囊结石形成的危险因素。维吾尔族在脂代谢方面异常情况更加突出,对胆囊结石发生具有重要意义。更多还原

【Abstract】 Objective To investigate the characteristics of lipid metabolism during in Kashgar, Xinjiang Uygur and Han gallstone formation, and to explore their ethnic differences. Methods We retrospectively collected 240 cases in our hospital diagnosed gallstone patients four lipid parameters were measured, including 120 cases of Uygur, Han 120 cases, while 240 cases detected(Han and Uygur each 120 cases) healthy blood lipid four indicators as control. Results The patients with gallstone serum cholesterol, triglycerides, lowdensity lipoprotein was significantly higher(P< 0.05), high density lipoprotein(HDL-C) was significantly lower than the control group(P < 0.05), the difference statistically significant. Uighur gallstone patients with serum cholesterol, triglycerides, LDL higher than the Han gallstone patients(P < 0.05), high density lipoprotein(HDL-C) were significantly lower than the Han group(P < 0.05)The difference was statistically significant. Conclusion Serum TC, TG, LDL concentration, HDLC concentration and decreased lipid metabolism are risk factors for gallstone formation. Uighurs in lipid metabolism abnormalities more prominent, the occurrence of gallstones is important.更多还原