【摘要】 目的探讨非ST段抬高急性冠状动脉综合征(NSTE-ACS)患者全球急性冠状动脉事件注册(GRACE)评分与血浆脑钠肽(BNP)、髓过氧化酶(myeloperoxidase,MPO)水平的相关性。方法入选120例在我院住院的NSTE-ACS患者,临床预测变量对其进行GRACE危险评分积分,并进行危险层次分层,入院后测定血浆BNP、MPO水平。分析其与GRACE危险积分不同层次之间的关系。结果①血浆BNP、MPO水平与GRACE危险积分呈正相关(r=0.71,P<0.05);随着GRACE危险积分评分值增加,患者血浆BNP、MPO水平亦逐渐升高;②随访期主要心血管事件发生率也增多(P<0.05)。结论 GRACE积分与BNP、MPO水平呈正相关,并与NSTACS预后有关,能够对NSTEACS患者进行危险分层。更多还原

【Abstract】 Objective To investigate the correlation of GRACE risk score and plasma brain natriuretic pep-tide(BNP),myeloperoxidase in patients with non- ST segment elevation acute coronary syndrome.Methods Selected 120 cases in NSTE-ACS patients in our hospital,clinical predictors its GRACE risk score points and dangerous level stratification,determination of plasma BNP,MPO levels after admission.Analyze the relationship between the different levels between the GRACE risk score.Results(1)The GRACE risk score is positively correlated with the plasma BNP and MPO levels(r=0.71,P<0.05);(2) The incidence of MACE increased significantly with the rise of GRACE risk score and BNP,MPO levels.Conclusion:The higher GRACE risk score and BNP,MPO levels,the worse the prognosis,it could be use to predict the prognosis.更多还原